Clinical Research

Genizon has an extensive clinical recruiting network consisting of over 1,000 investigators and 250 nurses which recruit participants for Genizon's research program throughout Quebec. The clinical department represents ~30% of Genizon’s staff.

All studies are conducted prospectively and according to protocols specifically designed for individual diseases. Inclusion and exclusion criteria are designed in collaboration with expert clinicians, geneticists and statisticians. Extensive clinical and demographic data are collected for each study and have been important to many gene discoveries through sub-phenotype analyses. All clinical data are captured using eRT, a commercial clinical database management system, extensively customized by Genizon to manage genetic studies. All clinical activities are conducted in compliance with GCPs.

Over 47,000 participants have been recruited and have donated DNA under strict ethical procedures following IRB approval and informed consent. Over 160 approvals from 48 IRBs have been obtained. Clinical studies, protocols and informed consent forms are specially adapted for genetic studies, and are in compliance with Québec, Canadian, U.S. and international regulations and guidelines for ethical conduct of clinical and genetic studies.

See "Participants - Clinical Programs" for more information on our clinical programs.