Gene Expression
Genizon offers genome-wide expression studies in humans using intact or partially-degraded RNA samples (DASL assay) or in mice using intact RNA only.Genome-wide expression
Genizon uses Illumina's Genome-wide Expression BeadChips in its genome-wide expression services.
Highlights
- Full-length 50-mer probes provide better selectivity and sensitivity
- High feature density enables low sample and reagent volumes
- Feature redundancy (30X average) delivers high-confidence results
Genome-wide human expression
The Human-6 v2 and HumanRef-8 v2 Expression BeadChips allows high-confidence target discovery, disease classification, and pathway studies. Researchers can profile six or eight samples per BeadChip and more than 48,000 transcript probes per sample using the Human-6, or more than 22,000 transcript probes per sample using the HumanRef-8.
Genome-wide mouse expression
The Mouse-6 and MouseRef-8 Expression BeadChip allows high-confidence studies using this important model organism. Researchers can profile six samples per Mouse-6 BeadChip and more than 47,000 transcripts per sample. Researchers can profile eight samples per MouseRef-8 BeadChip and approximately 24,000 well-annotated RefSeq transcripts per sample.
DASL gene expression
The cDNA-mediated annealing, selection, extension, and ligation assay (DASL) is part of a powerful gene expression solution designed to generate reproducible profiles from degraded RNAs such as those derived from formalin-fixed, paraffin-embedded (FFPE) tissues. The DASL assay can be used with the Human Cancer Panel targeting 502 genes or with a custom set of between 512 and 1,536 genes. The analyses are performed on one of two multi-sample array platforms, the Sentrix Universal-96 Array Matrix or Universal-16 BeadChip.
Highlights
- 1 - 3 sites per transcript; up to 512 - 1,536 genes per sample
- Redundant probe representation (average 30X)
- High sample-to-sample reproducibility (typical r2 > 0.99)
- Multi-sample array formats: 96 or 16 samples per microarray